New SEP Blocking Office 365 Login

I need a solution

Very strange issue here, we are using SEP with Seamless integration on WSS. I have upgraded my own machine from 14.2.4815.1101 to 14.2.5280.2000 and now when on WSS I cant login to my Office Online Apps like Word etc.

Any ideas on this I cannot roll out this version of SEP if it does this.

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